Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189018 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL9189011 | 0.75 | ACHE (0.32) | ACHE | |
| SCHEMBL9417133 | 0.74 | ACHE (0.36) | ACHEALDH1A1MAPTTDP1HDAC6 | |
| SCHEMBL9189989 | 0.73 | ACHE (0.33) | ACHE | |
| SCHEMBL22458325 | 0.73 | FGFR1 (0.45) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8708648 | 0.72 | ACHE (0.50) | ACHEFGFR1FGFR4 | |
| SCHEMBL9417203 | 0.72 | ACHE (0.31) | ACHE | |
| SCHEMBL9184008 | 0.72 | ACHE (0.33) | ACHEALDH1A1 | |
| SCHEMBL9187944 | 0.72 | — | — | |
| SCHEMBL9183998 | 0.72 | ACHE (0.33) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| EP-0773220-B1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-6187921-B1 | 2-AMINO-6-CHLOROPURINE HAVING DOUBLE CONE-LIKE CRYSTAL FORM CONSTRUCTED BY COMBINING TWO PYRAMIDS WITH EACH OTHER AT THEIR BOTTOMS AND HAVING SPECIFIED AVERAGE PARTICLE DIAMETER | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0967213-A1 | Process for preparing tetraalkylammonium salt of 6-halogenopurine derivative | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0543095-B1 | Method for producing 2-amino-6-halogenopurine and synthesis of an intermediate therefore | SUMIKA FINE CHEMICALS CO LTD (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5789590-A | Double cone-like crystal form of 2-amino-6-chloropurine and preparation | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0773220-A1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5440037-A | Method for production of 2-amino-6-halogenopurine derivatives | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5391733-A | Synthesis intermediates for 2-amino-6-halogenopurines | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5389637-A | 2-formylamino-6-halogenopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0543095-A2 | Method for producing 2-amino-6-halogenopurine and synthesis intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |