Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758009 | 0.80 | ADORA3 (0.63) | HSD17B10KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL2307829 | 0.79 | ADORA3 (0.65) | KDM4EKMT2AMAPTADORA2AADORA1 | |
| SCHEMBL4757988 | 0.77 | ADORA2A (0.65) | HSD17B10KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL1665926 | 0.76 | RAB9A (0.61) | HSD17B10KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL4759851 | 0.75 | ADORA3 (0.67) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL4759525 | 0.75 | ADORA2A (0.54) | HSD17B10KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL4758013 | 0.74 | ADORA3 (0.68) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL30230665 | 0.73 | ADORA2A (0.55) | HSD17B10KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL4759539 | 0.73 | ADORA3 (0.68) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL4758535 | 0.73 | ADORA3 (0.68) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448253-B1 | Adenosine A3 receptor modulators | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2002-09-10 | — | — | US | claimed |