Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644775 | 0.88 | SMN1; SMN2 (0.43) | L3MBTL1GAASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10394898 | 0.86 | L3MBTL1 (0.47) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9027815 | 0.86 | MAPT (0.44) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9026632 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9026833 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8802202 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8803624 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9027705 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9027396 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8077168 | 0.85 | MAPT (0.43) | MAPTL3MBTL1GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |