Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594917 | 0.88 | MAPT (0.44) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL10394898 | 0.83 | L3MBTL1 (0.47) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL8651149 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPK1L3MBTL1HSD17B10 | |
| SCHEMBL5085693 | 0.81 | L3MBTL1 (0.49) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL4749492 | 0.81 | L3MBTL1 (0.49) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL1495136 | 0.81 | L3MBTL1 (0.49) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL8359328 | 0.81 | L3MBTL1 (0.43) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL8359323 | 0.81 | L3MBTL1 (0.43) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL8952589 | 0.80 | L3MBTL1 (0.48) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL8952567 | 0.80 | L3MBTL1 (0.48) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | claimed |
| US-5807862-A | Therapeutic compounds containing pyrimidinyl moieties | CELL THERAPEUTICS, INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0746557-A4 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS INC (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0746557-A1 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0714302-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995022546-A1 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS, INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |