SCHEMBL230688

SCHEMBL230688

O=C(NCCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.72
EPHX2 P34913 1/20 0.52
FABP7 O15540 1/20 0.45
FABP5 Q01469 1/20 0.45
CASP3 P42574 2/20 0.44
HTT P42858 1/20 0.43
DOT1L Q8TEK3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468684 1.00 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31031901 1.00 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL1660910 0.96 KMT2A (0.74) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29401182 0.94 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL6889085 0.94 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29458423 0.94 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL887559 0.94 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.91 KMT2A (0.85) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL163534 0.91 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL8273302 0.90 KMT2A (0.63) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
CN-118255678-A Ionizable lipid compound and application thereof 荣灿生物医药技术(上海)有限公司 2024-06-28 CN disclosed
WO-2024040169-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS THE UNIVERSITY OF CHICAGO (US) 2024-02-22 WO disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
EP-4212541-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES AND THEIR INTERMEDIATES Genzyme Corporation (US) 2023-07-19 EP disclosed
US-20230167450-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-06-01 US disclosed
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-05-25 US disclosed
EP-0939629-A1 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1999-09-08 EP disclosed
EP-0789715-A4 COMPLEMENTARILY BONDED TWO- AND THREE-DIMENSIONAL SUPRAMOLECULAR STRUCTURES BURSTEIN LAB INC (US) 1999-08-18 EP disclosed
EP-0880503-A1 BALANOL ANALOGUES Phytera Symbion ApS (DK) 1998-12-02 EP disclosed
US-5718915-A DRUG DELIVERY BURSTEIN LABORATORIES, INC. (US) 1998-02-17 US disclosed
WO-1998003166-A1 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1998-01-29 WO disclosed
EP-0789715-A1 COMPLEMENTARILY BONDED TWO- AND THREE-DIMENSIONAL SUPRAMOLECULAR STRUCTURES BURSTEIN LABORATORIES, INC. (US) 1997-08-20 EP disclosed
WO-1997029091-A1 BALANOL ANALOGUES PHYTERA SYMBION APS (DK) 1997-08-14 WO disclosed
WO-1996032841-A9 NOVEL THERAPEUTIC BINDING MOLECULE COMPLEXES 1996-12-27 WO disclosed
WO-1996032841-A1 NOVEL THERAPEUTIC BINDING MOLECULE COMPLEXES BURSTEIN LABORATORIES, INC. (US) 1996-10-24 WO disclosed
WO-1996013522-A1 COMPLEMENTARILY BONDED TWO- AND THREE-DIMENSIONAL SUPRAMOLECULAR STRUCTURES BURSTEIN LABORATORIES, INC. (US) 1996-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, SNRPE, DDX21 KMT2A 3463/4885EPHX2 1615/4885FABP7 820/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 KMT2A 2167/4885EPHX2 2080/4885FABP7 1242/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.