Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796667 | 0.71 | TLR4 (0.30) | TLR4 | |
| SCHEMBL1809622 | 0.70 | SOAT1 (0.32) | TLR4 | |
| SCHEMBL13585913 | 0.68 | KDM1A (0.38) | TLR4CA1CA9 | |
| SCHEMBL9235827 | 0.68 | TLR4 (0.38) | TLR4 | |
| SCHEMBL1803256 | 0.68 | SOAT1 (0.50) | KMT2A | |
| SCHEMBL30381700 | 0.65 | MEN1 (0.30) | KMT2A | |
| SCHEMBL9231126 | 0.61 | TLR4 (0.32) | TLR4 | |
| SCHEMBL11370663 | 0.61 | MAOA (0.34) | TLR4 | |
| SCHEMBL3232469 | 0.61 | — | — | |
| SCHEMBL7644421 | 0.60 | TLR4 (0.50) | TLR4CA1CA2CA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997037665-A1 | METHOD OF TREATING HEART FAILURE WITH ENDOTHELIN ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-10-16 | — | — | WO | claimed |
| US-12048316-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2024-07-30 | — | — | US | disclosed |
| US-12029228-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC Natural Products Co., Ltd (CN) | 2024-07-09 | — | — | US | disclosed |
| US-11985994-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC Natural Products Co., Ltd (CN) | 2024-05-21 | — | — | US | disclosed |
| US-11849742-B2 | Tasteful natural sweetener and flavor | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2023-12-26 | — | — | US | disclosed |
| US-11793218-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11751593-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC Natural Products Co., Ltd (CN) | 2023-09-12 | — | — | US | disclosed |
| EP-4223146-A1 | SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF | EPC Natural Products Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| US-20230085263-A1 | TASTEFUL NATURAL SWEETENER AND FLAVOR | EPC Natural Products., Ltd. (CN) | 2023-03-16 | — | — | US | disclosed |
| US-20230082165-A1 | TASTEFUL NATURAL SWEETENER AND FLAVOR | EPC Natural Products Co., Ltd (CN) | 2023-03-16 | — | — | US | disclosed |
| US-20190343155-A1 | SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF | EPC Natural Products Co., Ltd (CN) | 2019-11-14 | — | — | US | disclosed |
| WO-2019217269-A1 | A TASTEFUL NATURAL SWEETENER AND FLAVOR | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019217258-A1 | A TASTEFUL NATURAL SWEETENER AND FLAVOR | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019010263-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2019-01-10 | — | — | WO | disclosed |
| EP-0690054-B1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5587486-A | CONDENSATION; CARBONYLATION; HYDROLYSIS; INTERMEDIATES IN THE PRODUCTION OF MEDICINAL AND AGRICULTURAL AGENTS | KURARAY CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0690054-A1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO., LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |
| EP-0101004-B2 | PROCESS FOR PREPARING 4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0101004-B1 | PROCESS FOR PREPARING 4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-01-21 | — | — | EP | disclosed |
| EP-0101004-A1 | Process for preparing 4-oxo-4, 5, 6, 7-tetrahydroindole derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1984-02-22 | — | — | EP | disclosed |