Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2063435 | 0.90 | BTK (0.38) | KMT2AMEN1GAAKDM4EBTK | |
| SCHEMBL2064235 | 0.83 | KDM2B (0.36) | KMT2AGAAKDM4EBTKALDH1A1 | |
| SCHEMBL2064459 | 0.81 | HTR6 (0.46) | KDM4EBTKALDH1A1POLB | |
| SCHEMBL2064415 | 0.81 | BTK (0.35) | KDM4EBTKTSHR | |
| SCHEMBL2064496 | 0.74 | ELANE (0.38) | KMT2AMEN1HSD17B10KDM4ETSHR | |
| SCHEMBL7006378 | 0.70 | HTR6 (0.44) | KMT2AMEN1GAAALDH1A1POLB | |
| SCHEMBL7006379 | 0.70 | HTR6 (0.44) | KMT2AMEN1GAAALDH1A1POLB | |
| SCHEMBL2064263 | 0.69 | HTR6 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL2064750 | 0.66 | HTR6 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL2064466 | 0.66 | HTR6 (0.47) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |