Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165364 | 0.86 | CNR2 (0.34) | P2RX7MAPT | |
| SCHEMBL30518974 | 0.82 | FAAH (0.43) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2626945 | 0.82 | FAAH (0.43) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL25410597 | 0.82 | FAAH (0.43) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL25317885 | 0.82 | FAAH (0.43) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7601488 | 0.79 | ELANE (0.37) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2626926 | 0.79 | MAPT (0.38) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL15763281 | 0.78 | ALDH1A1 (0.32) | P2RX7ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL25320640 | 0.77 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL25320643 | 0.77 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346615-B1 | SPIROADAMANTYL DIOXETANES BEARING AN ALKOXY SUBSTITUENT, AND AN AROMATIC SUBSTITUENT ON THE DIOXETANE RING CAN BE ACTIVATED TO CHEMILUMINESCE IF THE AROMATIC SUBSTITUENT BEARS A MOIETY THAT IS CLEAVED BY AN ENZYME | TROPIX, INC. | 2002-02-12 | — | — | US | disclosed |
| EP-0649417-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649417-A4 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES. | TROPIX INC (US) | 1995-02-27 | — | — | EP | disclosed |
| WO-1994026726-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1994-11-24 | — | — | WO | disclosed |