Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594276 | 0.87 | MTNR1A (0.51) | KDM4EALDH1A1HPGDGAACA12 | |
| SCHEMBL17766183 | 0.85 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDNFE2L2CA12 | |
| SCHEMBL9109781 | 0.75 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HPGDNFE2L2CA12 | |
| SCHEMBL7419329 | 0.70 | MTNR1A (0.56) | KDM4EALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL28340761 | 0.70 | CA12 (0.44) | KDM4EALDH1A1HPGDNFE2L2MEN1 | |
| SCHEMBL29503038 | 0.69 | NPC1 (0.50) | KDM4EALDH1A1HPGDNFE2L2MEN1 | |
| SCHEMBL8502908 | 0.69 | NPC1 (0.50) | KDM4EALDH1A1HPGDNFE2L2MEN1 | |
| SCHEMBL8425830 | 0.69 | SMN1; SMN2 (0.45) | KDM4EALDH1A1HPGDNFE2L2CA12 | |
| SCHEMBL21624227 | 0.69 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31676773 | 0.69 | CA12 (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781280-B1 | DERIVATIVES OF BENZOPYRAN AND OF BENZOTHIOPYRAN, THEIR PREPARATION AND THEIR USE AS AGONISTS OF DOPAMINERGIC RECEPTORS | ZAMBON SPA (IT) | 2002-11-06 | — | — | EP | disclosed |