Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.72 |
| ▸ | PGR | P06401 | 7/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.72 |
| ▸ | AR | P10275 | 6/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286638 | 0.94 | NR3C1 (0.70) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11424936 | 0.93 | NR3C1 (0.79) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11286219 | 0.92 | NR3C1 (0.68) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL7209349 | 0.92 | NR3C1 (0.69) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11289697 | 0.92 | NR3C1 (0.72) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11438871 | 0.92 | NR3C1 (0.68) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11423833 | 0.92 | NR3C1 (0.87) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL4219065 | 0.91 | NR3C1 (0.69) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL4219068 | 0.91 | NR3C1 (0.69) | NR3C1PGRCYP3A4ARHIF1A | |
| SCHEMBL11429154 | 0.91 | NR3C1 (0.75) | NR3C1PGRCYP3A4ARHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640616-B1 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-5608093-A | ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0640616-A2 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |