SCHEMBL7595117

SCHEMBL7595117

CC(C)c1c(S(=O)(=O)O)c(C(C)C)c2cccc(C(C)C)c2c1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
GABRA1 P14867 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
CYP1A2 P05177 2/20 0.36
FAAH O00519 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
GABRB1 P18505 1/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326670 0.91 FABP3 (0.41) FABP3FABP4FABP5GABRA1GABRG2
SCHEMBL6272853 0.91 FABP3 (0.41) FABP3FABP4FABP5GABRA1GABRG2
SCHEMBL7594587 0.80 FABP3 (0.40) FABP3FABP4FABP5CYP1A2LMNA
SCHEMBL5149395 0.78 FABP3 (0.39) FABP3FABP4FABP5CYP1A2LMNA
SCHEMBL5149379 0.78 FABP3 (0.39) FABP3FABP4FABP5CYP1A2LMNA
SCHEMBL12482675 0.78 FABP3 (0.49) FABP3FABP4FABP5GABRA1GABRG2
SCHEMBL10710755 0.77 GABRA1 (0.43) GABRA1GABRG2GABRB3CYP1A2FAAH
SCHEMBL1358607 0.76 GABRA1 (0.41) GABRA1GABRG2GABRB3CYP1A2FAAH
SCHEMBL2742118 0.75 FABP3 (0.61) FABP3FABP4FABP5GABRA1GABRG2
SCHEMBL11144703 0.74 FABP3 (0.44) FABP3FABP4FABP5GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953871-B1 Photographic element containing yellow dye-forming photographic coupler EASTMAN KODAK CO (US) 2002-06-26 EP disclosed
US-6083677-A BASED ON AN ANNULATED HETEROCYCLIC KETOACETAMIDO COMPOUND. EASTMAN KODAK COMPANY (US) 2000-07-04 US disclosed
EP-0953871-A1 Photographic element containing yellow dye-forming photographic coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed