Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710755 | 0.98 | GABRA1 (0.43) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL7923602 | 0.84 | GABRA1 (0.39) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL7923598 | 0.77 | CYP2A6 (0.44) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL7595117 | 0.76 | FABP3 (0.41) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL6272853 | 0.76 | FABP3 (0.41) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL6326670 | 0.72 | FABP3 (0.41) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL1070380 | 0.71 | KIF11 (0.40) | GABRA1LMNAGABRB2CYP1A2HPGD | |
| SCHEMBL30381967 | 0.71 | GABRA1 (0.57) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL66227 | 0.71 | GABRA1 (0.57) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL4657600 | 0.71 | GABRA1 (0.57) | GABRA1LMNAGABRG2GABRB3GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580211-B1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| EP-2331535-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| EP-2331515-B1 | INSCETICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-10 | — | — | EP | disclosed |
| EP-2518068-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-2297136-B1 | INSECTICIDAL PYRIDYLPIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-28 | — | — | EP | disclosed |
| US-20110288131-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| EP-2260708-A2 | Insecticidal mixture containing gamma-cyhalothrin | Syngenta Limited (GB) | 2010-12-15 | — | — | EP | disclosed |
| US-6548233-B1 | Comprising a hydrophilic binder and a non-crystalline reducing agent for reducing silver ions, can be formulated in aqueous coating compositions to provide photothermographic materials | EASTMAN KODAK COMPANY | 2003-04-15 | — | — | US | disclosed |
| EP-0858261-B1 | PROCESS FOR THE PREPARATION OF A GRANULE | SYNGENTA LTD (GB) | 2001-07-25 | — | — | EP | disclosed |
| EP-1035431-A1 | Cyan coupler and combination solvent-containing photographic element and process | EASTMAN KODAK COMPANY (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5004494-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-02 | — | — | US | disclosed |
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |
| EP-0207590-A2 | Substituted azolyl ethanol derivatives as plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-07 | — | — | EP | disclosed |
| EP-0206523-A1 | Heterocyclic compounds as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4496388-A | FUNGICIDES; PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-29 | — | — | US | disclosed |
| EP-0028465-A1 | Acylanilide compounds, methods for their preparation, compositions containing them, and processes for combatting fungi | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
| EP-0015639-A2 | Enantiomers of triazole compounds, a process for preparing them, their use as plant fungicides and growth regulating agents and compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288131-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, ITPR3 | GABRA1 3431/4885LMNA 1380/4885GABRG2 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.