Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.70 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595534 | 1.00 | ITGB3 (0.70) | ITGB3ITGA2BITGAVHDAC1NAMPT | |
| SCHEMBL7600102 | 0.94 | ITGB3 (0.65) | ITGB3ITGA2BITGAVHDAC1NAMPT | |
| SCHEMBL7600109 | 0.94 | ITGB3 (0.65) | ITGB3ITGA2BITGAVHDAC1NAMPT | |
| SCHEMBL7600644 | 0.85 | ITGB3 (0.83) | ITGB3ITGA2BITGAVALDH1A1MAPT | |
| SCHEMBL7393761 | 0.85 | ITGB3 (0.83) | ITGB3ITGA2BITGAVALDH1A1MAPT | |
| SCHEMBL7593946 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7595440 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL7595444 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL7593955 | 0.81 | ITGB3 (0.79) | ITGB3ITGA2BITGAVMAPTKDM4E | |
| SCHEMBL7399925 | 0.80 | ITGB3 (0.77) | ITGB3ITGA2BITGAVALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |