Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.65 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600109 | 1.00 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCCKBRHDAC1 | |
| SCHEMBL7595534 | 0.94 | ITGB3 (0.70) | ITGB3ITGA2BITGAVHDAC1NAMPT | |
| SCHEMBL7595536 | 0.94 | ITGB3 (0.70) | ITGB3ITGA2BITGAVHDAC1NAMPT | |
| SCHEMBL7399925 | 0.85 | ITGB3 (0.77) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7595085 | 0.85 | ITGB3 (0.77) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7393761 | 0.81 | ITGB3 (0.83) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7600644 | 0.81 | ITGB3 (0.83) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7593946 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7599947 | 0.78 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7400533 | 0.77 | CCKBR (0.49) | ITGB3ITGA2BCCKBRBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |