Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28083209 | 0.85 | ALDH1A1 (0.37) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| SCHEMBL28862679 | 0.83 | ALOX15 (0.37) | HSD17B10ALOX15 | |
| Itaconate SCHEMBL27781638 | 0.82 | HSD17B10 (0.67) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL27571924 | 0.82 | HSD17B10 (0.45) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| Itaconate SCHEMBL6367963 | 0.82 | HSD17B10 (0.67) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL10544130 | 0.82 | HSD17B10 (0.45) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL7518321 | 0.82 | HCAR2 (0.39) | HSD17B10ALOX15HCAR2KEAP1NFE2L2 | |
| Acrylic Acid SCHEMBL28862680 | 0.81 | ALOX15 (0.50) | HSD17B10ALOX15ALDH1A1LMNA | |
| SCHEMBL83312 | 0.81 | — | — | |
| SCHEMBL6018777 | 0.81 | ALOX15 (0.48) | HSD17B10ALOX15TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254652-A1 | Poly(vinyl acetamide) adhesive for skin cleaning tape | National Starch and Chemical Investment Holding Corporation (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6228487-B1 | REMOVAL KERATOTIC PLUGS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-05-08 | — | — | US | disclosed |
| US-6207176-B1 | STARCH ON BACKING | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-03-27 | — | — | US | disclosed |