Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589652 | 0.85 | TDP1 (0.32) | TDP1AR | |
| SCHEMBL7594178 | 0.78 | TDP1 (0.37) | TDP1ARPRKCAGAA | |
| SCHEMBL7986009 | 0.77 | TDP1 (0.36) | TDP1ARPRKCAGAA | |
| SCHEMBL7590263 | 0.74 | TDP1 (0.31) | TDP1AR | |
| SCHEMBL7589643 | 0.72 | SMN1; SMN2 (0.38) | TDP1AR | |
| SCHEMBL7595750 | 0.72 | TDP1 (0.32) | TDP1ARPRKCA | |
| SCHEMBL29032607 | 0.70 | LMNA (0.40) | TDP1AR | |
| Triacetin SCHEMBL3870 | 0.69 | TDP1 (0.56) | TDP1ARPRKCAGAA | |
| Triacetin SCHEMBL821340 | 0.69 | TDP1 (0.56) | TDP1ARPRKCAGAA | |
| SCHEMBL7468028 | 0.68 | TDP1 (0.50) | TDP1ARPRKCAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |