Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986029 | 0.89 | LMNA (0.35) | TDP1 | |
| SCHEMBL7594178 | 0.84 | TDP1 (0.37) | TDP1ARPRKCAGAA | |
| SCHEMBL29032607 | 0.83 | LMNA (0.40) | TDP1AR | |
| SCHEMBL9009392 | 0.79 | TDP1 (0.33) | TDP1ARPRKCA | |
| SCHEMBL7595758 | 0.77 | TDP1 (0.34) | TDP1ARPRKCAGAA | |
| SCHEMBL28222617 | 0.76 | AR (0.36) | TDP1ARGAA | |
| SCHEMBL28227271 | 0.75 | AR (0.39) | TDP1ARGAA | |
| SCHEMBL28880448 | 0.75 | LMNA (0.36) | TDP1AR | |
| SCHEMBL8743496 | 0.75 | AR (0.31) | TDP1AR | |
| SCHEMBL7595750 | 0.74 | TDP1 (0.32) | TDP1ARPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354842-A | Improved preparation method of iomeprol and application of iomeprol in preparation | 重庆圣华曦药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115160174-A | Synthesis method of ioversol | 浙江海洲制药有限公司 | 2022-10-11 | — | — | CN | claimed |
| EP-0640067-B1 | IMPROVED SYNTHESIS OF IOVERSOL | MALLINCKRODT MEDICAL INC (US) | 1997-03-12 | — | — | EP | claimed |
| EP-0640067-A4 | IMPROVED SYNTHESIS OF IOVERSOL. | MALLINCKRODT MEDICAL INC (US) | 1995-05-31 | — | — | EP | claimed |
| EP-0640067-A1 | IMPROVED SYNTHESIS OF IOVERSOL. | MALLINCKRODT MEDICAL INC (US) | 1995-03-01 | — | — | EP | claimed |
| WO-1993023365-A1 | IMPROVED SYNTHESIS OF IOVERSOL | MALLINCKRODT MEDICAL, INC. (US) | 1993-11-25 | — | — | WO | claimed |
| EP-0513063-A1 | PROCESS FOR PRODUCTION OF IOVERSOL. | MALLINCKRODT INC (US) | 1992-11-19 | — | — | EP | claimed |
| US-4997983-A | Process for production of ioversol | MALLINCKRODT, INC. (US) | 1991-03-05 | — | — | US | claimed |
| CN-113816868-B | Synthesis method of iohexol | 浙江海洲制药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116354842-A | Improved preparation method of iomeprol and application of iomeprol in preparation | 重庆圣华曦药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116253660-A | Synthesis method of iohexol | 辽宁药联制药有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253660-A | Synthesis method of iohexol | 辽宁药联制药有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115160174-A | Synthesis method of ioversol | 浙江海洲制药有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-113816868-A | Synthesis method of iohexol | 浙江海洲制药有限公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-0513063-B1 | PROCESS FOR PRODUCTION OF IOVERSOL | MALLINCKRODT INC (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994027956-A1 | PURIFICATION OF 1,1,2-TRICHLOROETHANE | MALLINCKRODT MEDICAL, INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0516050-A2 | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures | BRACCO INTERNATIONAL B.V. (NL) | 1992-12-02 | — | — | EP | disclosed |
| EP-0513063-A1 | PROCESS FOR PRODUCTION OF IOVERSOL. | MALLINCKRODT INC (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991011431-A1 | PROCESS FOR PRODUCTION OF IOVERSOL | MALLINCKRODT, INC. (US) | 1991-08-08 | — | — | WO | disclosed |
| US-4997983-A | Process for production of ioversol | MALLINCKRODT, INC. (US) | 1991-03-05 | — | — | US | disclosed |