Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590661 | 0.96 | TSHR (0.53) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL7592037 | 0.91 | ALDH1A1 (0.49) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL1893480 | 0.88 | TSHR (0.57) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL7589051 | 0.84 | TSHR (0.46) | TSHRTDP1L3MBTL1TP53ALDH1A1 | |
| SCHEMBL9414652 | 0.84 | ESR1 (0.60) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL7591679 | 0.81 | ESR1 (0.55) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL9414654 | 0.78 | TSHR (0.47) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL19795490 | 0.78 | ALDH1A1 (0.55) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL9850701 | 0.77 | TSHR (0.55) | TSHRTDP1L3MBTL1ESR1CYP3A4 | |
| SCHEMBL7592390 | 0.77 | ESR1 (0.55) | TSHRTDP1L3MBTL1ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968994-B1 | PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF | UBE INDUSTRIES (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6307091-B1 | TRIFLUOROMETHYLATING A TRIFLUOROIODOBENZOIC ACID ESTER WITH ADIFLUORO(FLUOROSULFONYL)ACETIC ACID ESTER IN THE PRESENCE OF A COPPER CATALYST IN AN ORGANIC SOLVENT. | UBE INDUSTRIES, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| US-6160171-A | Trifluoro-substituted benzoic acid, esters thereof, and process for producing the same | UBE INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0968994-A1 | SUBSTITUTED TRIFLUOROBENZOIC ACIDS, ESTERS THEREOF, AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES, LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |