Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686129 | 0.86 | ALDH1A1 (0.46) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL686277 | 0.86 | ALDH1A1 (0.46) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL686279 | 0.83 | MAPT (0.45) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL17589167 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL685842 | 0.81 | ALDH1A1 (0.40) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL6028694 | 0.79 | MAPT (0.52) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL22323590 | 0.79 | MAPT (0.52) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL22324061 | 0.79 | MAPT (0.52) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL27963467 | 0.78 | KDM4E (0.47) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL12345830 | 0.78 | MAPT (0.40) | MAPTALDH1A1POLBLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384265-B1 | ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| EP-1169291-A1 | METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000056696-A1 | METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-28 | — | — | WO | disclosed |