SCHEMBL7596175

SCHEMBL7596175

C=CCN(CCN(CC=C)C(N)=O)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
DPP4 P27487 2/20 0.36
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.31
LMNA P02545 2/20 0.30
KDM4E B2RXH2 2/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3652188 0.90 ALDH1A1 (0.52) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL569861 0.90 ALDH1A1 (0.52) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL27529568 0.87 ALDH1A1 (0.50) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8008506 0.87 ALDH1A1 (0.42) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9519262 0.85 ALDH1A1 (0.45) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11632120 0.83
SCHEMBL29333 0.82 ZDHHC20 (0.45) ALDH1A1DPP4TSHRMEN1KMT2A
SCHEMBL11085445 0.80 ZDHHC20 (0.47) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7354267 0.79 ALDH1A1 (0.43) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7171007 0.78 ALDH1A1 (0.42) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0198345-B1 PROCESS FOR PRODUCING 1,3-DIALKYL-2-IMIDAZOLIDINONE MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-01 EP claimed
US-4731453-A Process for producing 1, 3-dialkyl-2-imidazolidinone MITSUI TOATSU CHEMICALS, INC. (JP) 1988-03-15 US claimed
EP-0823427-B1 Process for the preparation of high purity 1,3-dialkyl-2-imidazolidinone MITSUI CHEMICALS INC (JP) 2002-10-09 EP disclosed
US-5872260-A High purity 1,3-dialkyl-2-imidazolidinone and preparation process of same MITSUI CHEMICALS, INC. (JP) 1999-02-16 US disclosed
EP-0823427-A1 High purity 1,3-dialkyl-2-imidazolidinone and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-02-11 EP disclosed
EP-0198345-B1 PROCESS FOR PRODUCING 1,3-DIALKYL-2-IMIDAZOLIDINONE MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-01 EP disclosed
US-4731453-A Process for producing 1, 3-dialkyl-2-imidazolidinone MITSUI TOATSU CHEMICALS, INC. (JP) 1988-03-15 US disclosed
US-4731453-A Process for producing 1, 3-dialkyl-2-imidazolidinone MITSUI TOATSU CHEMICALS, INC. (JP) 1988-03-15 US disclosed
EP-0198345-A1 Process for producing 1,3-dialkyl-2-imidazolidinone MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-10-22 EP disclosed
EP-0198345-A1 Process for producing 1,3-dialkyl-2-imidazolidinone MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-10-22 EP disclosed