Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.60 |
| ▸ | CPA3 | P15088 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12207239 | 0.89 | MME (0.57) | NAALAD2MMEACENPSR1CYP1A2 | |
| SCHEMBL7596254 | 0.89 | MME (0.57) | NAALAD2MMEACENPSR1CYP1A2 | |
| SCHEMBL17261299 | 0.87 | NAALAD2 (0.50) | NAALAD2MMENPSR1SIGMAR1CYP1A2 | |
| SCHEMBL27699637 | 0.84 | MME (0.56) | NAALAD2MMEACENPSR1PTPN1 | |
| SCHEMBL995917 | 0.84 | NPSR1 (0.55) | NAALAD2MMENPSR1CYP1A2 | |
| SCHEMBL27699635 | 0.84 | MME (0.56) | NAALAD2MMEACENPSR1PTPN1 | |
| SCHEMBL20813981 | 0.84 | CA12 (0.50) | NAALAD2MMEACENPSR1SIGMAR1 | |
| SCHEMBL9291834 | 0.84 | CTSB (0.47) | NAALAD2MME | |
| SCHEMBL9291838 | 0.84 | CTSB (0.47) | NAALAD2MME | |
| SCHEMBL6423726 | 0.83 | GGT1 (0.57) | NAALAD2CPA3MMEACEKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | claimed |
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-2757093-B1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
| US-8883462-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2757093-A1 | GUANIDINOBENZOIC ACID COMPOUND | Astellas Pharma Inc. (JP) | 2014-07-23 | — | — | EP | disclosed |
| EP-2000540-B1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2508611-A1 | Process for production of triprenyl phenol compounds | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120100579-A1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-8110596-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-2000540-A9 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2000540-A2 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20060105375-A1 | Bioretrosynthetic methods for preparing products and compositions related thereto | VANDERBILT UNIVERSITY | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | SERPINB1, REN, SPINT2 | NAALAD2 174/4885CPA3 782/4885MME 20/4885 |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | PLAT, F2R, F12 | NAALAD2 1047/4885CPA3 141/4885MME 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.