Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000743 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL25254117 | 0.97 | OPRM1 (0.43) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL18324135 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL21436918 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL1333027 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL1001552 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL2507860 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL1335362 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL17879364 | 0.94 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL18107259 | 0.92 | DNM1 (0.52) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307116-B1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NAT RECH SCIENT (FR) | 2012-03-21 | — | — | EP | disclosed |
| EP-2307116-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | Centre National de la Recherche Scientifique - CNRS (FR) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009144419-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2009-12-03 | — | — | WO | disclosed |