SCHEMBL7596403

SCHEMBL7596403

Br[Zr](Br)(Br)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.48
TRPA1 O75762 1/20 0.48
CALM1 P0DP23 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
IDO1 P14902 3/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
TP53 P04637 1/20 0.41
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591882 0.82 TSHR (0.48) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL726480 0.82 TSHR (0.48) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL272369 0.75 CALM1 (0.50) TSHRALDH1A1TRPA1CALM1TDP1
Water SCHEMBL9141797 0.73 CALM1 (0.47) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL28833326 0.73 CALM1 (0.47) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL7593009 0.71 ALDH1A1 (0.46) TSHRALDH1A1TRPA1CALM1TDP1
Hydrochloric Acid SCHEMBL6668783 0.71 CALM1 (0.45) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL7595882 0.71 ALDH1A1 (0.46) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL7596414 0.71 ALDH1A1 (0.46) TSHRALDH1A1TRPA1CALM1TDP1
SCHEMBL5615183 0.71 CALM1 (0.45) TSHRALDH1A1TRPA1CALM1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694563-B1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON MITSUBISHI OIL CORP (JP) 2002-10-30 EP disclosed
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
US-6077804-A Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 2000-06-20 US disclosed
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
EP-0745616-B1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO LTD (JP) 1999-04-07 EP disclosed
US-5824618-A TITANIUM COMPOUND, GROUP 1-3 COMPOUND, ORGANOCYCLIC COMPOUND NIPPON OIL CO., LTD. (JP) 1998-10-20 US disclosed
US-5795839-A COORDINATION POLYMERIZATION CATALYST FOR POLYOLEFIN MANUFACTURE NIPPON OIL CO., LTD. (JP) 1998-08-18 US disclosed
US-5780562-A GROUP 4 METAL ALKOXIDE DERIVATIVES COMPLEXED WITH GROUP 1-3 METAL ALKOXIDE DERIVATIVES, ORGANOCYCLIC COMPOUNDS HAVING CONJUGATED BONDS, ALUMOXANES, AND A SLILICA OR ALUMINA NIPPON OIL CO., LTD. (JP) 1998-07-14 US disclosed
EP-0669346-B1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO LTD (JP) 1998-06-03 EP disclosed
US-5750454-A Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed
US-5451555-A Catalyst components for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1995-09-19 US disclosed
EP-0669346-A1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO. LTD. (JP) 1995-08-30 EP disclosed
US-5391660-A Narrow molecular weight distribution by addition polymerizing a olefin or mixtures in a catalysts mixtures having metal compounds, halometal compound and alumoxanes NIPPON OIL COMPANY, LIMITED (JP) 1995-02-21 US disclosed
US-5387567-A An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution NIPPON OIL CO., LTD. (JP) 1995-02-07 US disclosed
US-5331071-A Transition metal and alumoxane components NIPPON OIL CO., LTD. (JP) 1994-07-19 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed
EP-0520811-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0520816-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed