Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594768 | 0.81 | KMT2A (0.64) | KMT2AMEN1ATMPOLBALDH1A1 | |
| SCHEMBL6810873 | 0.77 | KMT2A (0.53) | KMT2AMEN1ATMPOLBALDH1A1 | |
| SCHEMBL6810866 | 0.73 | KMT2A (0.49) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL6811087 | 0.71 | KMT2A (0.57) | KMT2AMEN1ATMPOLBALDH1A1 | |
| SCHEMBL6811360 | 0.71 | KMT2A (0.67) | KMT2AMEN1ATMPOLBALDH1A1 | |
| SCHEMBL6812274 | 0.70 | KMT2A (0.54) | KMT2AMEN1ATMALDH1A1LMNA | |
| SCHEMBL6814684 | 0.70 | GPR139 (0.51) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL6814685 | 0.70 | KMT2A (0.69) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL6816768 | 0.69 | MEN1 (0.52) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL6815540 | 0.69 | LMNA (0.45) | KMT2AMEN1POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144399-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144399-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034261-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |