Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599789 | 0.88 | ALOX5 (0.32) | P2RX4REN | |
| SCHEMBL7595150 | 0.85 | APEX1 (0.37) | — | |
| SCHEMBL6766827 | 0.79 | P2RX4 (0.35) | P2RX4REN | |
| SCHEMBL7597615 | 0.78 | KMT2A (0.44) | — | |
| SCHEMBL7597716 | 0.78 | MTTP (0.35) | REN | |
| SCHEMBL6766394 | 0.74 | P2RX4 (0.34) | P2RX4REN | |
| SCHEMBL27732363 | 0.74 | ALDH1A1 (0.39) | P2RX4REN | |
| Hydrochloric Acid SCHEMBL6766830 | 0.73 | ALOX5 (0.33) | P2RX4REN | |
| SCHEMBL27732353 | 0.73 | KMT2A (0.39) | — | |
| SCHEMBL7595167 | 0.71 | APEX1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259492-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1255736-A2 | SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | Boehringer Ingelheim Pharma KG (DE) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001047899-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001047898-A2 | SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |