Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510017 | 0.91 | KDM1A (0.35) | KDM1AMEN1KMT2ANPSR1POLB | |
| SCHEMBL5691919 | 0.89 | MAPT (0.36) | KDM1AMEN1KMT2ANPSR1POLB | |
| SCHEMBL3877158 | 0.82 | P2RX7 (0.32) | MEN1KMT2AMAPT | |
| SCHEMBL5690785 | 0.81 | ENPP3 (0.36) | KDM1AMEN1KMT2ANPSR1MAPT | |
| SCHEMBL5690598 | 0.79 | MAPT (0.37) | KDM1AMEN1KMT2ANPSR1POLB | |
| SCHEMBL5691489 | 0.79 | ENPP3 (0.36) | KDM1AMEN1KMT2APOLBMAPT | |
| SCHEMBL7068178 | 0.77 | POLB (0.40) | MEN1KMT2ANPSR1POLB | |
| SCHEMBL7069483 | 0.75 | NPSR1 (0.41) | KMT2ANPSR1MAPT | |
| SCHEMBL5691009 | 0.74 | MAPT (0.40) | KMT2APOLBMAPT | |
| SCHEMBL7314567 | 0.73 | CYP2D6 (0.34) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-A1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006434-A1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS INC. (US) | 1999-02-11 | — | — | WO | claimed |