⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL10582765 | 0.97 | — | — | |
| Ethane SCHEMBL8949916 | 0.94 | KDM4E (0.35) | — | |
| Methylamine SCHEMBL9161547 | 0.91 | LAP3 (0.35) | — | |
| Pyridine SCHEMBL8706837 | 0.79 | TSHR (0.38) | — | |
| Toluene SCHEMBL8949748 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL9402428 | 0.75 | — | — | |
| SCHEMBL11693402 | 0.71 | — | — | |
| SCHEMBL14580424 | 0.69 | — | — | |
| Medronic Acid SCHEMBL7755429 | 0.69 | KDM4E (0.71) | — | |
| SCHEMBL14252385 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072965-C | Improved topical delivery of drugs | PROCTER & GAMBLE (US) | 2001-10-17 | — | — | CN | claimed |
| CN-1091317-A | Improve the part input of medicine | PROCTER & GAMBLE (US) | 1994-08-31 | — | — | CN | claimed |
| EP-0573604-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS. | NORWICH EATON PHARMA (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992014474-A1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-09-03 | — | — | WO | claimed |
| US-20230129793-A1 | KITS AND DEVICES | BIOFIDELITY LTD (GB) | 2023-04-27 | — | — | US | disclosed |
| CN-114945578-A | Compounds as CD73 inhibitors | 博奥阿迪斯生物科技公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-3377504-B1 | CYCLAM BASED COMPOUNDS, THEIR CONJUGATES, CO-ORDINATION COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, METHOD OF PREPARATION AND USE THEREOF | UNIV KARLOVA (CZ) | 2020-08-19 | — | — | EP | disclosed |
| US-8772268-B2 | Bisphosphonamidate prodrugs and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| WO-2009116044-A2 | COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2009-09-24 | — | — | WO | disclosed |
| WO-2001044260-A9 | NOVEL PURINES | ARIAD PHARMA INC (US) | 2002-07-04 | — | — | WO | disclosed |
| EP-1158987-A1 | METHODS OF INCREASING BONE VOLUME USING NON-NATURALLY-OCCURRING FP SELECTIVE AGONISTS AND ANTIRESORPTIVE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| CN-1072965-C | Improved topical delivery of drugs | PROCTER & GAMBLE (US) | 2001-10-17 | — | — | CN | disclosed |
| EP-0586521-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0537008-A1 | Use of biphosphonates for the manufacture of a medicament for blocking neoplastic transformation of cells induced by ras oncogenes | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0514124-A2 | Use of phosphonomethylphosphinate squalene synthetase inhibitors for the manufacture of a medicament for the lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0514124-A2 | Use of phosphonomethylphosphinate squalene synthetase inhibitors for the manufacture of a medicament for the lowering cholesterol | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0298553-A1 | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-01-11 | — | — | EP | disclosed |