SCHEMBL7597205

SCHEMBL7597205

Clc1cc2ncsc2cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
DYRK1A Q13627 2/20 0.39
STIM1 Q13586 1/20 0.39
ORAI1 Q96D31 1/20 0.39
POLB P06746 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD11B1 P28845 1/20 0.38
MAPK13 O15264 1/20 0.37
CDK1 P06493 1/20 0.37
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414890 1.00 ALDH1A1 (0.43) ALDH1A1HSD17B10NPC1RAB9ATDP1
Sulfuric Acid SCHEMBL28617618 0.88 NPC1 (0.42) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL1420652 0.85 GAA (0.44) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL722459 0.83 ALDH1A1 (0.38) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL6129384 0.83 ALDH1A1 (0.38) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL6068203 0.83 MAPT (0.43) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL4052274 0.83 RIPK2 (0.39) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL30490167 0.83 ALDH1A1 (0.38) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL4296143 0.82 ALDH1A1 (0.52) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL9116750 0.80 TRPM5 (0.37) ALDH1A1HSD17B10NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102782210-B Disperse azo dyes COLOURTEX IND LTD 2014-07-02 CN claimed
US-8409300-B2 Disperse azo dyes COLOURTEX INDUSTRIES LIMITED (IN) 2013-04-02 US claimed
US-20120291207-A1 DISPERSE AZO DYES COLOURTEX INDUSTRIES LIMITED (IN) 2012-11-22 US claimed
EP-0742477-B1 Spectrally sensitized photothermographic elements EASTMAN KODAK CO (US) 2002-12-11 EP claimed
US-5861424-A CATIONIC HETEROCYCLIC COMPOUNDS FOR TREATING CANCER DANA FARBER CANCER INSTITUTE (US) 1999-01-19 US claimed
EP-0742477-A1 Spectrally sensitized photothermographic elements EASTMAN KODAK COMPANY (US) 1996-11-13 EP claimed
EP-0742478-A1 Photothermographic elements containing a combination of spectral sensitizers EASTMAN KODAK COMPANY (US) 1996-11-13 EP claimed
US-5510236-A SPECTRALLY SENSITIZED WITH ANIONIC CYANINE DYE COMPRISING TWO THIAZOLE NUCLEI, AT LEAST ONE BEING 5,6-DIHALOBENZOTHIAZOLE NUCLEUS, EACH SUBSTITUTED WITH N-SULFOALKYL GROUP EASTMAN KODAK COMPANY (US) 1996-04-23 US claimed
US-5508162-A SUPPORT BEARING PHOTOSENSITIVE SILVER HALIDE, ORGANIC SILVER SALT, REDUCING AGENT; WHEREIN SILVER HALIDE IS SPECTRALLY SENSITIZED WITH COMBINATION OF CYANINE DYES, FIRST HAVING TWO THIAZOLE NUCLEI, SECOND HAVING THIAZOLE AND OXAZOLE NUCLEI EASTMAN KODAK COMPANY (US) 1996-04-16 US claimed
CN-115093723-B Amino naphthol type disazo heterocyclic disperse dye 南通大学 2023-11-28 CN disclosed
CN-115093723-A Amino naphthol type dual-azo-cycle disperse dye 南通大学 2022-09-23 CN disclosed
CN-113444378-B Bisazo heterocyclic disperse dye for alkaline dyeing and preparation method thereof 江南大学 2022-03-25 CN disclosed
CN-113444378-A Bisazo heterocyclic disperse dye for alkaline dyeing and preparation method thereof 江南大学 2021-09-28 CN disclosed
US-8409300-B2 Disperse azo dyes COLOURTEX INDUSTRIES LIMITED (IN) 2013-04-02 US disclosed
US-4047964-A BENZISOXAZOLE FUJI PHOTO FILM CO., LTD. (JA) 1977-09-13 US disclosed
US-4040841-A SENSITIZING DYE FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4035190-A 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-12 US disclosed
US-4018610-A Supersensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-04-19 US disclosed
US-3977883-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed
US-3967967-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-07-06 US disclosed