SCHEMBL7597221

SCHEMBL7597221

C=CCCCCCCCCC(=O)Oc1ccc(O)c(C=NCCNC=C(C=O)c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.33
KDM4E B2RXH2 3/20 0.33
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CA1 P00915 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7598392 0.88 ALDH1A1 (0.35) CA2KDM4EGAAALDH1A1TAAR1
SCHEMBL7596825 0.83 CA2 (0.43) CA2KDM4EGAAPRSS1PRSS2
SCHEMBL7596822 0.83 CA2 (0.43) CA2KDM4EGAAPRSS1PRSS2
SCHEMBL7597620 0.79 TP53 (0.36) CA2GAAALDH1A1LMNAMAPT
SCHEMBL7596265 0.74 KMT2A (0.48) CA2ALDH1A1TRPV1LMNAMAPT
SCHEMBL7597225 0.74 PRSS1 (0.32) PRSS1PRSS2PRSS3
SCHEMBL7597760 0.70 MEN1 (0.47) CA2HTTHPGDKMT2A
SCHEMBL28433913 0.68 ESR1 (0.48) HTTPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL24565376 0.67 PRSS1 (0.56) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL7587172 0.67 PRSS1 (0.56) PRSS1PRSS2PRSS3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927155-B1 METAL-CONTAINING SIDE CHAIN LIQUID CRYSTAL POLYMERS QINETIQ LTD (GB) 2002-11-20 EP disclosed
US-6184322-B1 USED IN DISPLAY TECHNOLOGY, THIN FILM MAGNETIC MATERIALS FOR USE IN DATA STORAGE, LUBRICANTS AND ANISOTROPICALLY SUPPORTED CATALYSTS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2001-02-06 US disclosed