Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.45 |
| ▸ | PGK1 | P00558 | 3/20 | 0.43 |
| ▸ | PGK2 | P07205 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597313 | 1.00 | CCNA2 (0.45) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL6835055 | 1.00 | CCNA2 (0.45) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL6841737 | 0.92 | PGK1 (0.43) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL6839274 | 0.90 | ADORA1 (0.51) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7597841 | 0.90 | ADORA1 (0.51) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7597844 | 0.90 | ADORA1 (0.51) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL6839334 | 0.87 | ADORA2A (0.54) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839161 | 0.87 | ADORA2A (0.51) | PGK1PGK2ADORA2AADORA3 | |
| SCHEMBL7601673 | 0.87 | ADORA2A (0.51) | PGK1PGK2ADORA2AADORA3 | |
| SCHEMBL7596792 | 0.86 | ADORA2A (0.52) | PGK1PGK2ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051425-B1 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-30 | — | — | EP | claimed |