Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 8/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118883 | 1.00 | CPB2 (0.55) | CPB2MMP2MMP9NPY1RNPY5R | |
| SCHEMBL8118882 | 1.00 | CPB2 (0.55) | CPB2MMP2MMP9NPY1RNPY5R | |
| SCHEMBL8121995 | 0.95 | NPY1R (0.52) | CPB2NPY1RNPY5RMMECTSD | |
| SCHEMBL7597310 | 0.95 | NPY1R (0.52) | CPB2NPY1RNPY5RMMECTSD | |
| SCHEMBL7597314 | 0.95 | NPY1R (0.52) | CPB2NPY1RNPY5RMMECTSD | |
| Hydrochloric Acid SCHEMBL9200911 | 0.94 | NPY1R (0.51) | CPB2NPY1RNPY5RMMECTSD | |
| SCHEMBL5317762 | 0.90 | NPY1R (0.53) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL8526459 | 0.85 | NPY1R (0.54) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL8120862 | 0.85 | NPY1R (0.54) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL5313786 | 0.85 | NPY1R (0.50) | NPY1RNPY5RMMECTSDNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175418-B | Pentacyclic indole quinolizine for inhibiting autophagy of cells, synthesis, antitumor activity and application thereof | 首都医科大学 | 2020-01-14 | — | — | CN | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |