SCHEMBL7597686

SCHEMBL7597686

C[Zr](C)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605523 0.85 HTR2A (0.33) HTR2ASIGMAR1HTR6
SCHEMBL62070 0.81 HTR2A (0.37) HTR2ASIGMAR1HTR6
SCHEMBL216461 0.80 HTR6 (0.31) HTR2AHTR6
SCHEMBL6918352 0.80 HTR6 (0.31) HTR2AHTR6
SCHEMBL7636151 0.79 HTR6 (0.30) HTR2AHTR6
SCHEMBL7632416 0.78 HTR2A (0.39) HTR2ASIGMAR1HTR6
SCHEMBL6918921 0.78
SCHEMBL28670525 0.76 HTR2A (0.38) HTR2ASIGMAR1HTR6
SCHEMBL7638051 0.75 SIGMAR1 (0.35) HTR2ASIGMAR1HTR6
SCHEMBL797124 0.75 SIGMAR1 (0.32) HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
EP-0849288-B1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORP (JP) 2002-11-27 EP disclosed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed