Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440635 | 0.91 | CTSS (0.52) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL7440638 | 0.91 | CTSS (0.52) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL7593159 | 0.86 | ACE (0.53) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL7273142 | 0.75 | ACE (0.65) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL7273147 | 0.75 | ACE (0.65) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL3554901 | 0.74 | ACE (0.63) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL31407807 | 0.74 | ACE (0.63) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL3554904 | 0.74 | ACE (0.63) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL3821386 | 0.74 | ACE (0.63) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL14232658 | 0.74 | ITGB3 (0.62) | CTSSCTSKCTSBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |