Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106747 | 0.91 | POLB (0.43) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7596376 | 0.84 | POLB (0.47) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL8111065 | 0.84 | POLB (0.49) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7602558 | 0.83 | POLB (0.46) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7599021 | 0.82 | POLB (0.45) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7602536 | 0.82 | L3MBTL1 (0.39) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7602577 | 0.81 | POLB (0.46) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7597987 | 0.78 | L3MBTL1 (0.36) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL8105519 | 0.78 | KMT2A (0.40) | POLBALDH1A1ADRA2CL3MBTL1ATM | |
| SCHEMBL7598974 | 0.77 | KMT2A (0.41) | POLBALDH1A1ADRA2CL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |