Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597990 | 0.91 | POLB (0.45) | POLBMTNR1BADRA2CL3MBTL1ATM | |
| SCHEMBL7602516 | 0.83 | L3MBTL1 (0.37) | POLBMTNR1BPTGDR2ADRA2CL3MBTL1 | |
| SCHEMBL7598300 | 0.81 | MTNR1B (0.48) | POLBMTNR1BPTGDR2ADRA2CL3MBTL1 | |
| SCHEMBL7602552 | 0.79 | MTNR1B (0.39) | POLBMTNR1BPTGDR2ADRA2CL3MBTL1 | |
| SCHEMBL7602164 | 0.79 | MTNR1B (0.39) | POLBMTNR1BPTGDR2ADRA2CL3MBTL1 | |
| SCHEMBL7601427 | 0.78 | MTNR1B (0.40) | POLBMTNR1BPTGDR2L3MBTL1ATM | |
| SCHEMBL7601939 | 0.77 | TDP1 (0.38) | MTNR1BPTGDR2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7601959 | 0.76 | PYGM (0.37) | MTNR1BPTGDR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7599476 | 0.75 | PTGDR2 (0.46) | POLBMTNR1BPTGDR2ADRA2CL3MBTL1 | |
| SCHEMBL7596376 | 0.74 | POLB (0.47) | POLBMTNR1BADRA2CL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |