SCHEMBL759827

SCHEMBL759827

C/C(N)=C/C(=O)OCCCCOC(=O)/C=C(/C)N

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 1/20 0.46
ATM Q13315 1/20 0.45
HCAR2 Q8TDS4 4/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
NAAA Q02083 1/20 0.34
EPHX1 P07099 1/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27956667 1.00 TSHR (0.46) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL11006969 0.98 TSHR (0.50) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL11003632 0.98 TSHR (0.50) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL11003628 0.98 TSHR (0.50) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL11006987 0.98 TSHR (0.50) TSHRALDH1A1CYP3A4ATMHCAR2
Ethylene Glycol SCHEMBL11055892 0.94 TSHR (0.42) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL9434812 0.92 HCAR2 (0.55) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL1318132 0.92 TSHR (0.45) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL10921977 0.92 ALDH1A1 (0.47) TSHRALDH1A1CYP3A4ATMHCAR2
SCHEMBL7430462 0.92 HCAR2 (0.55) TSHRALDH1A1CYP3A4ATMHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3323500-B1 MANUFACTURING METHOD FOR TRIPTYCENE POLYMER CARRIER FILM NANJING UNIVERSITY OF TECHNOLOGY (CN) 2021-01-27 EP claimed
US-10799836-B2 Preparation method for triptyl polymer separation membrane NANJING TECH UNIVERSITY (CN) 2020-10-13 US claimed
US-20180236408-A1 A PREPARATION METHOD FOR TRIPTYL POLYMER SEPARATION MEMBRANE NANJING TECH UNIVERSITY (CN) 2018-08-23 US claimed
EP-3323500-A1 MANUFACTURING METHOD FOR TRIPTYCENE POLYMER CARRIER FILM Nanjing Tech University (CN) 2018-05-23 EP claimed
EP-2045291-B1 VINYL CHLORIDE RESIN COMPOSITION ADEKA CORP (JP) 2015-02-18 EP claimed
US-8506854-B2 Stabilizer system for halogenated polymers NABALTEC AG (DE) 2013-08-13 US claimed
US-20110129628-A1 STABILIZER SYSTEM FOR HALOGENATED POLYMERS NABALTEC AG (DE) 2011-06-02 US claimed
EP-2178959-B1 STABILIZER SYSTEM FOR HALOGENATED POLYMERS NABALTEC AG (DE) 2011-01-19 EP claimed
EP-2178959-A1 STABILIZER SYSTEM FOR HALOGENATED POLYMERS Nabaltec AG (DE) 2010-04-28 EP claimed
EP-1913067-B1 STABILIZER COMPOSITIONS BASED ON GUANIDINE OR MELAMINE COMPOUNDS TO STABILIZE HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2009-10-07 EP claimed
WO-2009021652-A1 STABILIZER SYSTEM FOR HALOGENATED POLYMERS NABALTEC AG (DE) 2009-02-19 WO claimed
EP-1368423-B1 CHLORATE-CONTAINING STABILIZER SYSTEM WITH NITROGEN-CONTAINING SYNERGISTS FOR STABILIZING HALOGEN-CONTAINING POLYMERS CROMPTON VINYL ADDITIVES GMBH (DE) 2004-12-01 EP claimed
US-4161580-A Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage CIBA-GEIGY CORPORATION (US) 1979-07-17 US claimed
US-4089845-A Thermosetting mixtures which are stable on storage from polyimide and .beta. CIBA-GEIGY CORPORATION (US) 1978-05-16 US claimed
CN-116096772-A Reactive mixtures for producing polyurethane layers with heat-activatable catalyst systems 贝内克-凯利科股份公司 2023-05-09 CN disclosed
EP-3850040-B1 A STABILIZED CHLORINATED POLYVINYLCHLORIDE AND AN ARTICLE MADE THEREFROM REAGENS SPA (IT) 2023-04-19 EP disclosed
EP-3323500-B1 MANUFACTURING METHOD FOR TRIPTYCENE POLYMER CARRIER FILM NANJING UNIVERSITY OF TECHNOLOGY (CN) 2021-01-27 EP disclosed
US-4117029-A VINYL CHLORIDE POLYE NITTO KASEI CO. LTD. (JP) 1978-09-26 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4089845-A Thermosetting mixtures which are stable on storage from polyimide and .beta. CIBA-GEIGY CORPORATION (US) 1978-05-16 US disclosed