Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816328 | 0.84 | CA1 (0.39) | CA1CA2CA9CA12CA4 | |
| SCHEMBL253349 | 0.80 | CA2 (0.42) | CA1CA2CA9CA12CA4 | |
| SCHEMBL7166967 | 0.75 | CA1 (0.38) | CA1CA2CA9CA12CA4 | |
| SCHEMBL2357790 | 0.71 | CYP3A4 (0.41) | CA1CA2CA9GAAADORA2A | |
| SCHEMBL7462469 | 0.70 | CA1 (0.36) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1763134 | 0.70 | CYP3A4 (0.39) | CA1CA2CA9GAAALOX15 | |
| SCHEMBL11043924 | 0.69 | CYP3A4 (0.35) | CA1CA2CA9GAAADORA2A | |
| SCHEMBL11648570 | 0.68 | TSHR (0.30) | SMN1; SMN2TSHR | |
| SCHEMBL8516542 | 0.68 | ALOX15 (0.38) | CA1CA2CA9GAAALOX15 | |
| SCHEMBL8113334 | 0.68 | CYP3A4 (0.38) | CA1CA2CA9CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1176910-C | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives | - | 2004-11-24 | — | — | CN | disclosed |
| WO-2002081424-A2 | CHEMICAL COMPOUNDS DERIVED FROM OCTOPAMINE AND THEIR USES AS BETA 3-ADRENERGIC AGONISTS | MALAK JEAN CLEMENT EDOUARD GHI (BE) | 2002-10-17 | — | — | WO | disclosed |
| EP-0887346-A3 | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| EP-0887346-A2 | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-30 | — | — | EP | disclosed |
| CN-1203228-A | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives | HOFFMANN LA ROCHE (CH) | 1998-12-30 | — | — | CN | disclosed |