Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603048 | 0.89 | CYP1A2 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL7599610 | 0.88 | CYP1A2 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL7599792 | 0.87 | SMN1; SMN2 (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL7601066 | 0.84 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1POLBKMT2A | |
| SCHEMBL7602849 | 0.82 | CNR1 (0.50) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL7603821 | 0.81 | MAPT (0.53) | SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7601089 | 0.80 | TDP1 (0.51) | ALDH1A1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL7602716 | 0.77 | ALDH1A1 (0.53) | ALDH1A1NPC1SMN1; SMN2NPSR1POLB | |
| SCHEMBL7602651 | 0.76 | GAA (0.52) | ALDH1A1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL7601793 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPSR1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |