Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP16 | P51512 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601098 | 0.88 | TDP1 (0.48) | TDP1L3MBTL1RAB9APYGLKMT2A | |
| SCHEMBL7599610 | 0.81 | CYP1A2 (0.46) | RAB9APYGLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7602849 | 0.81 | CNR1 (0.50) | TDP1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL7598284 | 0.81 | GAA (0.50) | TDP1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL7603048 | 0.81 | CYP1A2 (0.53) | RAB9APYGLMAPTALDH1A1LMNA | |
| SCHEMBL7599792 | 0.81 | SMN1; SMN2 (0.45) | TDP1L3MBTL1RAB9APYGLKMT2A | |
| SCHEMBL7598422 | 0.80 | ALDH1A1 (0.48) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7603821 | 0.79 | MAPT (0.53) | TDP1L3MBTL1PYGLKMT2AMEN1 | |
| SCHEMBL7598919 | 0.79 | PRMT1 (0.56) | TDP1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7602893 | 0.76 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |