Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29106963 | 0.98 | NAAA (0.35) | MIFKIF11NAAAKEAP1NFE2L2 | |
| SCHEMBL11152541 | 0.95 | KIF11 (0.34) | MIFKIF11NAAAKEAP1NFE2L2 | |
| SCHEMBL692189 | 0.88 | KIF11 (0.32) | KIF11 | |
| SCHEMBL3882706 | 0.80 | NAAA (0.38) | MIFKIF11NAAAKEAP1NFE2L2 | |
| SCHEMBL132502 | 0.78 | KIF11 (0.31) | KIF11 | |
| Water SCHEMBL11440384 | 0.76 | — | — | |
| SCHEMBL7732599 | 0.76 | NAAA (0.35) | MIFNAAAMAOAMAOB | |
| SCHEMBL28984861 | 0.74 | MIF (0.35) | MIF | |
| SCHEMBL5892154 | 0.72 | CYP2C19 (0.33) | KIF11 | |
| SCHEMBL13133310 | 0.72 | KIF11 (0.34) | MIFKIF11NAAAKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395385-B1 | COMPRISING THE REACTION PRODUCT OF A POLYURETHANE PREPOLYMER AND A VINYL CHLORIDE BASED THERMOPLASTIC COPOLYMER; SHEAR THINNING RHEOLOGICAL BEHAVIOR, IMPROVED GREEN STRENGTH, WATER RESISTANCE, AND ADHESION TO VARIETY OF SUBSTRATES | ASHLAND INC | 2002-05-28 | — | — | US | disclosed |
| US-20020037415-A1 | Laminates prepared with reactive hot melt adhesive | ASHLAND INC. | 2002-03-28 | — | — | US | disclosed |
| US-6274674-B1 | SOLVENT-FREE; MOISTURE CURABLE | ASHLAND INC. | 2001-08-14 | — | — | US | disclosed |
| EP-1077809-A1 | REACTIVE HOT MELT ADHESIVE | ASHLAND INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000050236-A1 | REACTIVE HOT MELT ADHESIVE | ASHLAND INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| US-4822849-A | UNSATURATED POLYESTER | REICHHOLD CHEMICALS, INC. (US) | 1989-04-18 | — | — | US | disclosed |