Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.65 |
| ▸ | HTR6 | P50406 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | GBA1 | P04062 | 1/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | PRKCG | P05129 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | PRKCB | P05771 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10536254 | 0.98 | ESR1 (0.67) | ESR1GAAMAPTCYP2D6ESR2 | |
| SCHEMBL6057420 | 0.93 | ESR1 (0.59) | ESR1GAAMAPTCYP2D6ESR2 | |
| SCHEMBL11937428 | 0.92 | BCHE (0.65) | ESR1GAAMAPTBCHEACHE | |
| SCHEMBL9364383 | 0.91 | LSS (0.68) | ESR1GAABCHEACHEKDM4E | |
| SCHEMBL9097342 | 0.90 | EGFR (0.69) | ESR1GAAMAPTEGFRRAB9A | |
| SCHEMBL9360007 | 0.89 | LSS (0.70) | GAABCHEACHEKDM4EPPARA | |
| SCHEMBL9360140 | 0.89 | LSS (0.70) | GAABCHEACHEKDM4EPPARA | |
| SCHEMBL9360010 | 0.89 | LSS (0.70) | GAABCHEACHEKDM4EPPARA | |
| SCHEMBL9360056 | 0.89 | LSS (0.70) | GAABCHEACHEKDM4EPPARA | |
| SCHEMBL9360004 | 0.89 | LSS (0.70) | GAABCHEACHEKDM4EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111362816-B | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-111362816-A | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2020-07-03 | — | — | CN | claimed |
| EP-0126470-B1 | PROCESS FOR THE PREPARATION OF TAMOXIFEN | Bristol-Myers Company (US) | 1989-04-12 | — | — | EP | claimed |
| EP-0126470-A1 | Process for the preparation of tamoxifen | Bristol-Myers Company (US) | 1984-11-28 | — | — | EP | claimed |
| US-20230365490-A1 | METHODS FOR MAKING AND USING ENDOXIFEN | ATOSSA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230119640-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND | SHENZHEN UNIVERSITY (CN) | 2023-04-20 | — | — | US | disclosed |
| CN-111362816-B | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111362816-B | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111362816-A | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111362816-A | Preparation method of tamoxifen related substance | 扬子江药业集团江苏海慈生物药业有限公司 | 2020-07-03 | — | — | CN | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| EP-0126470-B1 | PROCESS FOR THE PREPARATION OF TAMOXIFEN | Bristol-Myers Company (US) | 1989-04-12 | — | — | EP | disclosed |
| EP-0168175-B1 | PREPARATION OF TAMOXIFEN | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0168175-A1 | Preparation of tamoxifen | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-15 | — | — | EP | disclosed |
| EP-0126470-A1 | Process for the preparation of tamoxifen | Bristol-Myers Company (US) | 1984-11-28 | — | — | EP | disclosed |
| EP-0126470-A1 | Process for the preparation of tamoxifen | Bristol-Myers Company (US) | 1984-11-28 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365490-A1 | METHODS FOR MAKING AND USING ENDOXIFEN | ESR1, CYP19A1, ESR2 | ESR1 1/4885GAA 3348/4885MAPT 4015/4885 |
| US-20230119640-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND | HIRA, NOD2, CHLSN | ESR1 1878/4885GAA 2168/4885MAPT 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.