Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.70 |
| ▸ | BCHE | P06276 | 7/20 | 0.67 |
| ▸ | ACHE | P22303 | 7/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PDE1A | P54750 | 5/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.60 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359814 | 1.00 | LSS (0.70) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL9360056 | 1.00 | LSS (0.70) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL9360004 | 1.00 | LSS (0.70) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL9360140 | 1.00 | LSS (0.70) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL9360007 | 1.00 | LSS (0.70) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL9364383 | 0.98 | LSS (0.68) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL11937428 | 0.94 | BCHE (0.65) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL7598659 | 0.89 | ESR1 (0.69) | LSSBCHEACHEPPARAKDM4E | |
| Hydrochloric Acid SCHEMBL10536254 | 0.88 | ESR1 (0.67) | LSSBCHEACHEPPARAKDM4E | |
| SCHEMBL6057567 | 0.88 | ALDH1A1 (0.63) | LSSBCHEACHEKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410359-B1 | Substituted aminoalkoxy-benzene-derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-26 | — | — | EP | disclosed |
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |