SCHEMBL7598744

SCHEMBL7598744

CC1=Cc2cc(Cc3ccccc3)ccc2C1[SiH](c1ccccc1)C1C(C)=Cc2cc(Cc3ccccc3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.35
CALM1 P0DP23 1/20 0.33
LTA4H P09960 1/20 0.33
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
OPRK1 P41145 1/20 0.32
SLC5A2 P31639 2/20 0.32
HNF4A P41235 1/20 0.31
LMNA P02545 1/20 0.31
PARP11 Q9NR21 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7039696 0.77 LMNA (0.31) LMNA
SCHEMBL28036485 0.69 IDH1 (0.40) IDH1CALM1LTA4HPRSS1PRSS2
SCHEMBL8085716 0.64 CALM1 (0.55) IDH1CALM1LTA4HPRSS1PRSS2
SCHEMBL15694827 0.64 CALM1 (0.55) IDH1CALM1LTA4HPRSS1PRSS2
SCHEMBL7598597 0.64
SCHEMBL7038357 0.64 KDM4E (0.35) LMNA
SCHEMBL7039516 0.64 PDCD1 (0.33)
SCHEMBL7613502 0.62 CALM1 (0.75) IDH1CALM1LTA4HPRSS1PRSS2
SCHEMBL13971231 0.62 CALM1 (0.75) IDH1CALM1LTA4HPRSS1PRSS2
SCHEMBL2938820 0.62 CALM1 (0.57) IDH1CALM1LTA4HPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1263847-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER Borealis Technology Oy (FI) 2002-12-11 EP disclosed
WO-2001062832-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER BOREALIS TECHNOLOGY OY (FI) 2001-08-30 WO disclosed