Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603452 | 0.89 | HSD17B10 (0.55) | HSD17B10MMP1MMP3 | |
| SCHEMBL8641490 | 0.89 | HSD17B10 (0.45) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7599751 | 0.87 | HSD17B10 (0.47) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7601877 | 0.85 | HSD17B10 (0.44) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7607450 | 0.83 | HSD17B10 (0.40) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7602114 | 0.82 | CTSV (0.40) | HSD17B10 | |
| SCHEMBL7598837 | 0.81 | HSD17B10 (0.39) | HSD17B10MMP1HDAC2MMP2MMP3 | |
| SCHEMBL8642472 | 0.79 | MMP3 (0.51) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7598806 | 0.79 | HSD17B10 (0.43) | HSD17B10MMP1MMP2MMP3 | |
| SCHEMBL7600024 | 0.79 | HSD17B10 (0.58) | HSD17B10MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |