SCHEMBL7598972

SCHEMBL7598972

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)N(C)S(C)(=O)=O)n1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
TTR P02766 1/20 0.39
PPOX P50336 1/20 0.39
THRB P10828 1/20 0.34
VDR P11473 1/20 0.34
MAPT P10636 3/20 0.34
NPSR1 Q6W5P4 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 2/20 0.34
ALOX12 P18054 1/20 0.34
CCR6 P51684 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.31
PDE5A O76074 2/20 0.31
PDE6D O43924 1/20 0.31
PDE6A P16499 1/20 0.31
PDE6G P18545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7591130 0.93 MEN1 (0.38) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7591206 0.92 KMT2A (0.47) MEN1KMT2ATDP1TTRPPOX
Flazasulfuron SCHEMBL7589736 0.92 MEN1 (0.39) MEN1KMT2ATDP1TTRPPOX
Flupyrsulfuron SCHEMBL7582081 0.91 MEN1 (0.40) MEN1KMT2ATDP1TTRPPOX
Fomesafen SCHEMBL7598763 0.91 KMT2A (0.41) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7592565 0.91 KMT2A (0.38) MEN1KMT2ATDP1TTRPPOX
SCHEMBL7591401 0.90 KMT2A (0.46) MEN1KMT2ATDP1TTRPPOX
Sulfosulfuron SCHEMBL7577290 0.87 MEN1 (0.35) MEN1KMT2ATDP1TTRPPOX
Bifenox SCHEMBL7595826 0.87 TDP1 (0.47) MEN1KMT2ATDP1TTRPPOX
Chlorsulfuron SCHEMBL7580717 0.86 KMT2A (0.38) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.