Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652725 | 0.84 | THRB (0.39) | THRBACLYFOLH1 | |
| SCHEMBL7596870 | 0.80 | CYP2D6 (0.31) | SLC22A6 | |
| SCHEMBL29263768 | 0.80 | THRB (0.39) | THRBACLYTDP1 | |
| SCHEMBL29263772 | 0.79 | THRB (0.41) | THRBACLY | |
| SCHEMBL30979237 | 0.79 | THRB (0.41) | THRBSLC22A6TDP1FOLH1SMN1; SMN2 | |
| SCHEMBL2222458 | 0.79 | CYP2D6 (0.30) | — | |
| SCHEMBL1704335 | 0.78 | SLC22A6 (0.38) | SLC22A6TDP1FOLH1SMN1; SMN2 | |
| SCHEMBL3132066 | 0.77 | MAPT (0.39) | THRB | |
| SCHEMBL19307810 | 0.77 | — | — | |
| SCHEMBL29203315 | 0.76 | MAPT (0.46) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981655-B1 | CHEMICAL VAPOUR DEPOSITION PRECURSORS | QINETIQ LTD (GB) | 2002-10-16 | — | — | EP | disclosed |
| EP-0981655-A2 | CHEMICAL VAPOUR DEPOSITION PRECURSORS | Secretary of State for Defence acting through his Defence Evaluation and Research Agency (GB) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051837-A2 | CHEMICAL VAPOUR DEPOSITION PRECURSORS | SECRETARY OF STATE FOR DEFENCE ACTING THROUGH HIS DEFENCE EVALUATION AND RESEARCH AGENCY (GB) | 1998-11-19 | — | — | WO | disclosed |