Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979237 | 0.82 | THRB (0.41) | SLC22A6TDP1SMN1; SMN2FOLH1 | |
| SCHEMBL16877270 | 0.80 | SLC22A6 (0.43) | SLC22A6TDP1SMN1; SMN2FOLH1GABRR1 | |
| SCHEMBL29211171 | 0.79 | SLC22A6 (0.41) | SLC22A6TDP1SMN1; SMN2FOLH1GABRR1 | |
| SCHEMBL7599047 | 0.78 | CYP2D6 (0.33) | SLC22A6TDP1SMN1; SMN2FOLH1TSHR | |
| SCHEMBL2180876 | 0.78 | TET2 (0.43) | — | |
| SCHEMBL7598977 | 0.78 | THRB (0.41) | SLC22A6TDP1SMN1; SMN2FOLH1 | |
| SCHEMBL28719269 | 0.75 | SLC22A6 (0.38) | SLC22A6TDP1SMN1; SMN2FOLH1GABRR1 | |
| SCHEMBL1271508 | 0.75 | SLC22A6 (0.38) | SLC22A6TDP1SMN1; SMN2FOLH1GABRR1 | |
| SCHEMBL7596870 | 0.74 | CYP2D6 (0.31) | SLC22A6TSHR | |
| SCHEMBL15402927 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440518-B1 | METHOD FOR MAKING FLUOROALKYL NITRILES | BAYER CROPSCIENCE AG (DE) | 2014-08-20 | — | — | EP | claimed |
| EP-2245001-B1 | Method for the production of 2-fluoroacyl-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | claimed |
| US-8288582-B2 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | claimed |
| US-8203015-B2 | Process for preparing fluoroalkyl nitriles | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | claimed |
| EP-2440518-A1 | METHOD FOR PRODUCING FLUOROALKYL NITRILES | Bayer Cropscience AG (DE) | 2012-04-18 | — | — | EP | claimed |
| WO-2010142377-A1 | METHOD FOR PRODUCING FLUOROALKYL NITRILES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-12-16 | — | — | WO | claimed |
| US-20100312002-A1 | Process For Preparing Fluoroalkyl Nitriles | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | claimed |
| CN-101903333-A | The method for preparing 2-fluorine acyl group-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG | 2010-12-01 | — | — | CN | claimed |
| EP-2245001-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | claimed |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | claimed |
| WO-2009083134-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-07-09 | — | — | WO | claimed |
| EP-2072497-A1 | Method for manufacturing 2-fluoracyl-3-amino-acrylic acid derivatives | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | claimed |
| EP-2440518-B1 | METHOD FOR MAKING FLUOROALKYL NITRILES | BAYER CROPSCIENCE AG (DE) | 2014-08-20 | — | — | EP | disclosed |
| CN-101903333-B | Method for manufacturing 2-fluoracyl-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG | 2013-11-06 | — | — | CN | disclosed |
| EP-2245001-B1 | Method for the production of 2-fluoroacyl-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-8288582-B2 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | disclosed |
| EP-2245001-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | disclosed |
| WO-2009083134-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-07-09 | — | — | WO | disclosed |
| EP-2072497-A1 | Method for manufacturing 2-fluoracyl-3-amino-acrylic acid derivatives | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100312002-A1 | Process For Preparing Fluoroalkyl Nitriles | PFAS, NAAA, NISCH | SLC22A6 3949/4885TDP1 3105/4885SMN1; SMN2 2726/4885 |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | AADAT, AADAC, ALAD | SLC22A6 2605/4885TDP1 2572/4885SMN1; SMN2 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.