SCHEMBL7599196

SCHEMBL7599196

Cc1cc(C)c(-c2ccc3c(c2)C([Hf](C)(C)C2c4cc(-c5cccc6ccccc56)ccc4-c4ccc(-c5cccc6ccccc56)cc42)c2cc(-c4c(C)cc(C)cc4C)ccc2-3)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.37
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
CA9 Q16790 5/20 0.37
CYP2A6 P11509 2/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
CYP1A2 P05177 1/20 0.36
MCL1 Q07820 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35
TLR8 Q9NR97 1/20 0.35
AVPR2 P30518 1/20 0.34
AVPR1A P37288 1/20 0.34
CHRNA1 P02708 1/20 0.33
CHRNG P07510 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL797656 0.83 CRHR1 (0.36) CA12CA1CA2CA9CYP2A6
Hydrochloric Acid SCHEMBL8606095 0.83 CA12 (0.39) CA12CA1CA2CA9CYP2A6
Hydrochloric Acid SCHEMBL7583797 0.83 CA12 (0.37) CA12CA1CA2CA9CYP2A6
SCHEMBL7601274 0.83 CA12 (0.37) CA12CA1CA2CA9CYP2A6
SCHEMBL796973 0.77 CRHR1 (0.36) CA12CA1CA2CA9EDNRB
SCHEMBL20609436 0.72 CYP2A6 (0.55) CA12CA1CA2CA9CYP2A6
SCHEMBL7599187 0.71 CA12 (0.34) CA12CA1CA2CA9CYP2A6
Methane SCHEMBL7937872 0.71 EGFR (0.34) CA12CA1CA2CA9CYP2A6
SCHEMBL5779310 0.68 MCL1 (0.46) CA12CA1CA2CA9CYP2A6
SCHEMBL7267293 0.67 CYP1A2 (0.46) CYP2A6CYP1A2ENPP3ENPP1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed