SCHEMBL759922

SCHEMBL759922

C=C(C)C(=O)OCC(C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C)OCCCOCCO

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755619 0.90 TSHR (0.40) TSHRTHRB
SCHEMBL3679697 0.82 TSHR (0.40) TSHRTHRB
SCHEMBL663825 0.81 TSHR (0.36) TSHRTHRB
SCHEMBL755513 0.81 TSHR (0.40) TSHRTHRB
SCHEMBL759924 0.79 TSHR (0.34) TSHRTHRB
SCHEMBL13417615 0.72 TSHR (0.39) TSHRTHRB
SCHEMBL18176162 0.72 TSHR (0.39) TSHRTHRB
SCHEMBL25771180 0.72 TSHR (0.56) TSHRTHRB
SCHEMBL18784855 0.72 TSHR (0.46) TSHRTHRB
SCHEMBL12799607 0.71 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207825-B8 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2012-03-21 EP disclosed
EP-2207825-B1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2011-06-29 EP disclosed
EP-2207825-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS Johnson & Johnson Vision Care, Inc. (US) 2010-07-21 EP disclosed
WO-2009058207-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2009-05-07 WO disclosed
US-20090111905-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. 2009-04-30 US disclosed