Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759922 | 0.90 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL755513 | 0.90 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3679697 | 0.84 | TSHR (0.40) | TSHRTHRB | |
| SCHEMBL3674540 | 0.80 | TSHR (0.32) | TSHR | |
| SCHEMBL663825 | 0.78 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL755621 | 0.77 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL17805317 | 0.75 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL9301359 | 0.75 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL27823865 | 0.73 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL8862241 | 0.73 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807999-B2 | Siloxane monomer, composition for preparation of silicone hydrogel lens containing same, and silicone hydrogel lens | INTEROJO INC. (KR) | 2020-10-20 | — | — | US | claimed |
| EP-3418319-B1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | INTEROJO INC (KR) | 2020-04-15 | — | — | EP | claimed |
| US-20190085000-A1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | INTEROJO INC. (KR) | 2019-03-21 | — | — | US | claimed |
| EP-3418319-A1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | Interojo Inc. (KR) | 2018-12-26 | — | — | EP | claimed |
| EP-2207825-B8 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2012-03-21 | — | — | EP | claimed |
| EP-2207825-B1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2011-06-29 | — | — | EP | claimed |
| JP-2011502198-A | — | — | 2011-01-20 | — | — | JP | claimed |
| EP-2207825-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | Johnson & Johnson Vision Care, Inc. (US) | 2010-07-21 | — | — | EP | claimed |
| EP-1809344-B1 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-01-20 | — | — | EP | claimed |
| WO-2009058207-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-05-07 | — | — | WO | claimed |
| US-20090111905-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-04-30 | — | — | US | claimed |
| EP-3141943-B1 | HYDROGEL CONTACT LENS HAVING WET SURFACE, AND MANUFACTURING METHOD THEREFOR | INTEROJO INC (KR) | 2022-07-13 | — | — | EP | disclosed |
| US-10807999-B2 | Siloxane monomer, composition for preparation of silicone hydrogel lens containing same, and silicone hydrogel lens | INTEROJO INC. (KR) | 2020-10-20 | — | — | US | disclosed |
| EP-3418319-B1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | INTEROJO INC (KR) | 2020-04-15 | — | — | EP | disclosed |
| US-10371965-B2 | Hydrogel contact lens having wet surface, and manufacturing method therefor | INTEROJO INC. (KR) | 2019-08-06 | — | — | US | disclosed |
| EP-3418319-A1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | Interojo Inc. (KR) | 2018-12-26 | — | — | EP | disclosed |
| US-20170146823-A1 | HYDROGEL CONTACT LENS HAVING WET SURFACE, AND MANUFACTURING METHOD THEREFOR | INTEROJO INC. (KR) | 2017-05-25 | — | — | US | disclosed |
| EP-3141943-A1 | HYDROGEL CONTACT LENS HAVING WET SURFACE, AND MANUFACTURING METHOD THEREFOR | Interojo Inc. (KR) | 2017-03-15 | — | — | EP | disclosed |
| EP-2207825-B1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20090111905-A1 | PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085000-A1 | SILOXANE MONOMER, COMPOSITION FOR PREPARATION OF SILICONE HYDROGEL LENS CONTAINING SAME, AND SILICONE HYDROGEL LENS | SUMO1, SUMO2, SMCHD1 | TSHR 3748/4885THRB 4520/4885ALDH1A1 2833/4885 |
| US-10807999-B2 | Siloxane monomer, composition for preparation of silicone hydrogel lens containing same, and silicone hydrogel lens | SUMO1, SUMO2, SMCHD1 | TSHR 3748/4885THRB 4520/4885ALDH1A1 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.